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DC Field | Value | Language |
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dc.contributor.author | Carmona-Vargas, Christian C. | - |
dc.contributor.author | Ellena, Javier | - |
dc.contributor.author | D’Vries, Richard F. | - |
dc.contributor.author | Chaur, Manuel N. | - |
dc.date.accessioned | 2019-11-06T16:24:36Z | - |
dc.date.available | 2019-11-06T16:24:36Z | - |
dc.date.issued | 2019-03-19 | - |
dc.identifier.issn | 01035053 | - |
dc.identifier.uri | https://repository.usc.edu.co/handle/20.500.12421/2050 | - |
dc.description.abstract | Herein, we present the serendipitous obtaining of 7-chloro-2,3-dihydro-5H-thiazolo [3,2-a]pyrimidin-5-one in 40% yield by using POCl3 and a thiobarbituric acid derivative. The thiazolopyrimidine derivative was characterized by 1H nuclear magnetic resonance (NMR), UV-Vis, and Fourier transform infrared (FTIR) spectroscopy. Additionally, the structure was confirmed by single crystal X-ray diffraction, where it was found that the compound crystallizes in the P-1 triclinic space group with two conformeric molecules of 7-chloro-2,3-dihydro-5H-thiazolo [3,2-a]pyrimidin-5-one by asymmetric unit. Also, from the structural data was studied the supramolecular interactions using Hirshfeld surface analysis and 2D fingerprint plots. © 2019 Sociedade Brasileira de Química | es |
dc.language.iso | en | es |
dc.publisher | Sociedade Brasileira de Quimica | es |
dc.subject | Chlorination | es |
dc.subject | Serendipity | es |
dc.subject | Thiazolopyrimidine | es |
dc.subject | Thiobarbituric acid | es |
dc.title | When serendipity knocks on the door: Synthesis and Physicochemical Characterization of 7-Chloro-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one | es |
dc.type | Article | es |
Appears in Collections: | Artículos Científicos |
Files in This Item:
File | Description | Size | Format | |
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When serendipity knocks on the door Synthesis and Physicochemical Characterization of 7-Chloro-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one.pdf | 2.03 MB | Adobe PDF | View/Open |
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