Polímeros de coordinación de plata(I), cobalto(II) y manganeso(II) con PVA inmovilizado en quitosano depositado en aluminio y vidrio erosionado

Abstract

The aim of this research work was the development of low and medium molecular weight chitosan (Q) membranes embedded with polyvinyl alcohol, which were enriched with the metal ions of: copper (II), cobalt (II), manganese ( II) and silver (I) as new bactericidal materials. The method used was electrospinning, establishing optimal deposit conditions (DC 11 cm, VB 0.01 mL / hr, V 16 Kv, T 70 min and 16% PVA) on two aluminum surfaces and eroded glass. The antibacterial activity was carried out against Staphylococcus aureus and Eschericia Coli by comparing the activity in solution and its corresponding supported membrane. The method used was Kirby - Bauer modified discs, implementing as positive controls amoxicillin at 25000 ppm and the metal salts at 50000 ppm by each transition metals. The preliminary results show bactericidal and bacteriostatic activity mediated by the nature of the metal ion, further studies are proposed in order to understand the diffusion process and the effect on the stability of the coordination polymers with respect to biological activity.