Protein profile of different cellular fractions from Mycobacterium tuberculosis strains after exposure to isoniazid

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DC Field	Value	Language
dc.contributor.author	Nieto Ramirez, Luisa María	-
dc.contributor.author	Mehaffy, Carolina	-
dc.contributor.author	Dobos, Karen M.	-
dc.date.accessioned	2019-07-09T22:23:08Z	-
dc.date.available	2019-07-09T22:23:08Z	-
dc.date.issued	2019-04-17	-
dc.identifier.issn	23523409	-
dc.identifier.uri	https://repository.usc.edu.co/handle/20.500.12421/328	-
dc.description.abstract	Different biochemical studies looking for the effect of INH on the physiology of Mycobacterium tuberculosis (Mtb)have been conducted. Here, we present a detailed analysis, looking at the protein variation in the Mtb cell due to exposure of sub-inhibitory concentrations of INH, evaluating three different variables: cellular fraction, genetic lineage, and INH phenotypic profile. Mass spectrometry analysis demonstrated that the most significantly affected cellular fraction was the membrane and the INH resistant strains showed the highest number of proteins altered when they were exposed to INH. Raw data are available via ProteomeXchange with identifier PXD007588. © 2019 The Authors	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier Inc.	en_US
dc.title	Protein profile of different cellular fractions from Mycobacterium tuberculosis strains after exposure to isoniazid	en_US
dc.type	Article	en_US
Appears in Collections:	Artículos Científicos

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