“Actividad antifúngica de alpinia zerumbet frente a mohos y levaduras de importancia clínica”

Abstract

Invasive fungal diseases (EFI) diseases to susceptible hosts, cause high impact morbidity and mortality, associated with the high resistance to antimycotics of the agents etiological associated with this pathology. The antifungal activity of extracts of Alpinia zerumbet, vs. C. albicans, C. parapsilosis, C. krusei, Aspergillus fumigatus, A. terreus and Fusarium oxysporum was determined. The minimum inhibitory concentration (MIC) method and minimum inhibitory fungal concentration (CFI) based on NTC 2455 was used. As control sample, Fluconazole standard is considered and 96% Ethanol as a control. The alcoholic and hydroalcoholic extracts of the leaves and flowers affected good fungistatic and fungicidal activity when compared to the control and standard sample. It is concluded that the leaves compounds and flowers of A. zerumbet are promising for future research looking for compounds with antimicrobial activity for use in agriculture, food, and treatment of systemic mycosis.