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dc.contributor.authorCarmona-Vargas, Christian C.-
dc.contributor.authorEllena, Javier-
dc.contributor.authorD’Vries, Richard F.-
dc.contributor.authorChaur, Manuel N.-
dc.date.accessioned2019-08-05T21:51:05Z-
dc.date.available2019-08-05T21:51:05Z-
dc.date.issued2019-
dc.identifier.issn1678-4790-
dc.identifier.urihttps://repository.usc.edu.co/handle/20.500.12421/471-
dc.description.abstractHerein, we present the serendipitous obtaining of 7-chloro-2,3-dihydro-5H-thiazolo [3,2-a]pyrimidin-5-one in 40% yield by using POCl3 and a thiobarbituric acid derivative. The thiazolopyrimidine derivative was characterized by 1H nuclear magnetic resonance (NMR), UV-Vis, and Fourier transform infrared (FTIR) spectroscopy. Additionally, the structure was confirmed by single crystal X-ray diffraction, where it was found that the compound crystallizes in the P-1 triclinic space group with two conformeric molecules of 7-chloro-2,3-dihydro-5H-thiazolo [3,2-a]pyrimidin-5-one by asymmetric unit. Also, from the structural data was studied the supramolecular interactions using Hirshfeld surface analysis and 2D fingerprint plots.en_US
dc.language.isoenen_US
dc.publisherJournal of the Brazilian Chemical Societyen_US
dc.subjectchlorinationen_US
dc.subjectthiobarbituric aciden_US
dc.subjectserendipityen_US
dc.subjectthiazolopyrimidineen_US
dc.titleWhen Serendipity Knocks on the Door: Synthesis and Physicochemical Characterization of 7-Chloro-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-oneen_US
dc.typeArticleen_US
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